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DiscussionFrostySemax31

coming off GLP-1s and weight regain?

So guys, I've been digging into some trial data about what happens when people stop GLP-1s like sema and tirz. Seems like weight regain is a biggie. In one study, folks regained up to 2/3 of lost weight within a year after stopping. Yikes! Anyone here seen similar patterns or got tips on how to handle maintenance? Do other peptides help stabilize things post-GLP-1?

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ZZestyRetatrutide1434 min ago
That rebound's rough! Maybe cagri can step in for maintenance? Different pathway so might mix it up. Anyone pairing it with GLP-1s post-cycle? Curious if survo or mazdu offer any long-term help too.